Department of Health Research, Ministry of Health and Family Welfare, Government of India
स्वास्थ्य अनुसंधान विभाग, स्वास्थ्य और परिवार कल्याण मंत्रालय, भारत सरकार
Field of Research:
Research focus is on the development of novel vaccine candidate
against enteric pathogens like Vibrio cholerae,
Shigella, Salmonella, Escherichia coli, and
Campylobacter for the livestock and human.
Laboratory has identified a number of potential vaccine
candidates like outer membrane vesicles, heat killed bacteria,
live attenuated bacteria, chitosan-alginate nanoparticle.
Special expertise on outer membrane vesicles based studies on
various animal models, like Mouse, Rat, Guinea pig, Rabbit,
Chicken and Zebra fish.
Long path programme of the laboratory is to develop a single
vaccine candidate against all enteric pathogens.
Educational Background:
In 1992, after completion of Master degree in Human Physiology from Dept. of Physiology, University College of Science & Technology, Calcutta University, he joined Division of Bacteriology, National Institute of Cholera and Enteric Diseases (NICED), an integral Institute of the Indian Council of Medical Research and a WHO Collaborating Centre for Research and Training in Diarrhoeal Diseases, Kolkata, India, for Ph. D. degree under supervision of Dr. GB Nair. In 1996, he joined as Associate Professor in Dept. of Physiology, College of Medical Sciences-Nepal, where he devoted himself entirely in teaching medical students. Meanwhile, Dr. Koley got an opportunity for Post-Doctoral research in the laboratory of Prof Dipak K Sarkar, Dept Animal Sciences, Rutgers - The State University of New Jersey, New Brunswick, USA. After completion of one year in Rutgers University, Dr. Koley moved to Boston, joined Gastroenterology Section of Harvard Medical School, as Research Associate and worked there on "Molecular mechanism of Barrett's oesophagus and to identify therapeutic target for Adenocarcinoma" under leadership of Prof. R K Goyal, renowned gastroenterologist.
Research Achievement:
Published 70 original papers and 40 abstracts in his credit.
Secured patent for a process for the preparation of Cholera Vaccine-VA1.3 (European Patent Office; Patent No.- 97309957.5-2105 on 19/05/98) in pre-doctoral research in NICED
Received Young Scientist Award in IUPS International Congress, Christchurch, New Zealand, August 2001.
Awarded Oration Lecture: "Dr. (Mrs.) Chitralekha Mukherjee Memorial Oration-2010" and given lecture at St. John's Medical College, Bangalore on 16th December 2010
Recently developed Shigella Vaccine and applied patent through Indian council of Medical Research, New Delhi. Patent application for: "A multiple outer membrane vesicles (MOMV) of Shigellae as a Novel Candidate vaccine" ICMR New Delhi. (Patent application no. 1652/Del/2013 dated 31.05.2013)
International patent application: PCT patent application titled ‘A Multi-Serotype Outer Membrane Vesicles (MOMV) of shigellae as a novel candidate vaccine' (PCT/IN2014/000369).
Patent application for: "Alginate chitosan Nano formulation of
Omp-A, a Shigella protein subunit vaccine" ICMR New Delhi.
(Patent application # 201611015219/ IPR/NICED/OmpA/329 June,
2015)
Invited special lecture at "Asian Society of Diarrhoeal Disease
and Nutrition" conference (ASCODD) at Kochi between October
30,2017 to November 1, 2017.
Invited Lecture on "Shigella Vaccine" Occasion of MSD-Hilleman
Laboratory Science day workshop on 2nd Nov 2017 at Imperial
Hotel, New Delhi.
Name | Dr. Hemanta Koley |
---|---|
Designation | Scientist E |
Date of joining ICMR | 1st October 2004 |
Date of joining present post | 1st September 2016 |
Discipline | Physiologist |
Division | Bacteriology |
Specialization | Bacteriologist |
Email : | hemantakoley@hotmail.com |
Academic Qualification | |
Graduation | BSc in Physiology. |
Post Graduation | MSc in Physiology |
Doctoral | Physiology |
In 1992, after completion of Master degree in Human
Physiology from Dept. of Physiology, University College
of Science & Technology, University of Calcutta, Hemanta
Koley joined the Division of Bacteriology, National
Institute of Cholera and Enteric Diseases (NICED), an
integral Institute of the Indian Council of Medical
Research and a WHO Collaborating Centre for Research and
Training in Diarrhoeal Diseases, Kolkata, India, for Ph.
D. degree under supervision of Dr. GB Nair. In 1996, he
joined as Associate Professor in Dept. of Physiology,
College of Medical Sciences-Nepal, where he devoted
himself entirely in teaching medical students.
Meanwhile, Dr. Koley got an opportunity for
Post-doctoral research in the laboratory of Prof Dipak K
Sarkar, Dept Animal Sciences, Rutgers -The State
University of New Jersey, New Brunswick, USA. After
completion of one year in Rutgers University, Dr. Koley
moved to Boston, joined Gastroenterology Section of
Harvard Medical School, as Research Associate and worked
there on "Molecular mechanism of Barrett's oesophagus
and to identify therapeutic target for adenocarcinoma"
under leadership of Prof.. R K Goyal, renowned
gastroenterologist.In the year of 2004, 1st October, he
came back India and joined the Division of Bacteriology,
National Institute of Cholera and Enteric Diseases (NICED),
Kolkata, and has been since devotedly working on
development of a single vaccine against all circulating
enteric organisms.
Laboratory has identified a number of potential vaccine
candidates like outer membrane vesicles, heat killed
bacterial antigen, live attenuated bacterial antigen,
chitosan-alginate ompAnanoparticle.
Research focus is on the development of novel vaccine
candidate for the livestock and human against enteric
pathogens like Vibrio Cholerae, Shigella,
Salmonella,Escherichia coli, and Campylobacter.
Special expertise on outer membrane vesicles based
studies on various animal models, like Mouse, Rat,
Guinea pig, Rabbit, Chicken and Zebra fish.
Long path programme of the laboratory is to develop a
single vaccine candidate against all enteric pathogens.
National Membership: